ITGA4 antibody (PE)

Catalog No. ABIN951338

The Rat Monoclonal anti-ITGA4 antibody has been validated for FACS. It is suitable to detect ITGA4 in samples from Mouse.

Quick Overview for ITGA4 antibody (PE) (ABIN951338)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGA4 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: R1-2

Product Details anti-ITGA4 Antibody (PE)

Specificity: This CD49d Monoclonal Antibody reacts with Alpha-4 integrin (CD49d/ITGA4).

Purification: Protein G Chromatography

Immunogen: Peyers Patch HEV binding lymphoma line (TK1). Donor: Fisher Spleen. Fusion Partner: P3x63Ag8.653.

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name: CD49d / ITGA4

Background: CD49d helps to mediate cell-cell and cell-matrix interactions. Alpha-4 integrin combines with b1 and b7 integrin to form VLA-4 and LPAM-1 (Peyers patch homing receptor) respectively. VLA-4 is expressed on most peripheral lymphocytes, thymocytes and monocytes. LPAM-1 is found on peripheral lymphocytes, but few thymocytes. Fibronectin and VCAM-1 act as ligands for both VLA-4 and LPAM-1. LPAM-1 also binds the mucosal vascular addressin MAdCAM-1. (1)Synonyms: CD49 antigen-like family member D, Integrin alpha-4, Integrin alpha-IV, VLA-4, VLA4

Gene ID: 16401

NCBI Accession: NP_034706

UniProt: Q00651

Pathways: Integrin Complex